Pesquisa sobre:
STAT5 TRANSCRIPTION FACTOR
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DeCS
Descritor
Inglês
:
STAT5 Transcription Factor
Descritor
Espanhol
:
Factor de Transcripción STAT5
Descritor
Português
:
Fator de Transcrição STAT5
Categoria:
D12.644.360.024.342.500
D12.776.157.057.186.500
D12.776.476.024.421.500
D12.776.930.840.500
Definição
Inglês
:
A signal transducer and activator of transcription that mediates cellular responses to a variety of
CYTOKINES
. Stat5 activation is associated with transcription of
CELL CYCLE
regulators such as CYCLIN KINASE INHIBITOR P21 and anti-apoptotic genes such as BCL-2 GENES. Stat5 is constitutively activated in many
patients
with acute MYELOID
LEUKEMIA.
Nota Histórica
Inglês
:
2006(1992)
Qualificadores Permitidos
Inglês
:
AD
administration & dosage
AE
adverse effects
AG
agonists
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
CT
contraindications
DF
deficiency
DU
diagnostic use
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Número do Registro:
50798
Identificador Único:
D050799
Ocorrência na BVS
:
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CID-10
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